Relaxant effect of 7-ethoxy-4-methyl-2H-chromen-2-one by calcium channel blockade: computational and ex vivo studies
نویسندگان
چکیده
Amanda Sánchez-Recillas, Gabriel Navarrete-Vázquez, César Millán-Pacheco, Berenice Aguilar-Guadarrama, Rolffy Ortiz-Andrade, Samuel Estrada-Soto Facultad de Farmacia, Facultad de Ciencias and Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Colonia Chamilpa, C.P. 62209. Cuernavaca, Morelos, México. Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Calle 421 No. 41 x 26 y 28 Col. Industrial, C.P. 97150 Mérida Yucatán 97150, México.
منابع مشابه
Synthesis and antimicrobial activity of some derivatives of (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide.
(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (2) was prepared from (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester (1) and 100% hydrazine hydrate. Compound 2, is the key intermediate for the synthesis of several series of new compounds such as Schiff's bases 3a-l, formic acid N'-[2-(7-hydroxy-2-oxo-2H- chromen-4-yl)acetyl] hydrazide (4), acetic acid N'-[2-(7-hydroxy-2-oxo-2...
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